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The modern approach is to cut out obvious tumors — because lumps big enough to detect may be too dense for drugs and radiation to destroy — and to use radiation and chemotherapy to wipe out microscopic disease in other places.
This occurs because with a large sample size the power is big enough to detect, as statistically significant, irrelevant small differences.
No trial was big enough to detect the likely increase of survival, which is 5%.
Recalculating the power with the variances obtained in the study shows that the size of the study was big enough to detect 0.5 SD changes with more than 80% power, as intended.
Either our sample size was not big enough to detect a difference (as we had 162 in our study and Roberts et al. had a sample size of 462) or the reported difference in the original study was spurious.
Two explanations are possible: the deficits of these patients were too mild to be improved with the programs or there may have been a type II error, i.e., the sample was not big enough to detect differences in neuropsychological data.
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Admittedly, the sample size of our family collection, although among the largest GD family collections worldwide, was still not big enough to always detect genuine association alleles with moderate effect sizes.
Countrywide, the nation's biggest mortgage lender, disputes that it did not do enough to detect any problems earlier, noting that the bank that originated the loans, People's Choice, was contractually obligated to vet and check the loans.
Measuring about 1 part in 100,000, the variations were smaller than many theories had predicted and just big enough to be detected, Smoot recalls.
However, in the faint glow of the red ultracool dwarf stars, the effect of the biomarkers should be big enough to be detected.
The lower frequency of selection of other mutants may reflect a decreased ability of other eEF-2 variants to support protein synthesis, thereby causing a greater growth defect, and decreasing the chance that a colony will grow big enough to be detected and picked.
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big enough to play
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big enough to eat
big enough to stop
big enough to contain
big enough to take
big enough to satisfy
big enough to make
big enough to talk
big enough to guard
big enough to fight
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