The big challenges, in the bottom two quadrants, require action now.
Still, the big challenges in Afghanistan this year are more legal and political.
Rich as it is, Gazprom faces big challenges in the Medvedev era.
Mrs. Merkel faces big challenges in her second term in both domestic and foreign policy.
When given a full account of a threat, the American people have risen to big challenges in the past.
"These are big challenges in the development of these technologies," Livermore says, "but I'm convinced they'll come through gradually".
Generating a character through simple algorithms and then trying to make it rounded and real enough to generate emotions is one of the big challenges in modern computing.
The English designer Sir Paul Smith says that one of the big challenges in expanding his fashion and products empire is ensuring that each new store feels unique.
"That's how I've tackled all the big challenges in my life – be it putting myself through college, be it health challenges.
Most police chiefs realize the advantages of a department that represents the local community, but there are big challenges in recruiting more minority officers.
"But despite the reduced scale of cuts in the immediate future, there are still big challenges in implementation if the plans are to be achieved," he said.
