The bigger challenge is to start up a big venture that just happens to be small at first.
When asked, "What is the biggest challenge to supporting start-ups?" Hashim Shawa, Chairman and General Manager of the Bank of Palestine, answered, "Well, the occupation is clearly the main obstacle.
The biggest challenge is to start a business based on an open-source project that wouldn't actually kill the open source project and scare away the community.
Honigman: One of the biggest challenges to initially starting the Dinah was negotiating with the conservative stakeholders in Palms Springs.
They have no illusions about the challenges to starting a big tech company in Israel, as industries have changed and globalization has shifted many VCs' focus to bigger, sexier markets like India and China.
In an admission of the faults of New Labour, he said: "The biggest challenge to this country did not start with this government: how to make the economy not just for the top.
With its mission to "report on physical, structural, racial and cultural violations in Myanmar", Kamayut's approach is a bigger challenge to the authorities than other start-ups.
Banking and access to capital has always been one of the biggest challenges to cannabis start-ups.
I spoke to Guy Raz, the host, co-creator and editorial director of the TED Radio Hour and How I Built This on NPR, about why he started a podcast focused on entrepreneurship, the differences between hosting a podcast compared to a radio show, what he's learned from speaking to famous entrepreneurs, the big challenge with starting a business and his best advice to you.
Question from the audience: "Is this the biggest technical challenge for Facebook to date?" Bosworth: "This was definitely a big challenge, don't want to start a nerd fight by saying it was the biggest".
