(1) Transforming growth factor (TGF -β family proTGF -βare representative proteins that possess bidirectional roles during tumor progression.
Recently, a bidirectional regulatory role of MAP kinase for neutrophil migration has been demonstrated where the activation of p38 molecule enhanced the chemokine-mediated neutrophil migration, while the activation of ERK pathway inhibited their migration [ 50].
In this study, they have utilized a potent chemokine, fMLP, to show the bidirectional regulatory roles of MAP kinases that mediated through the G-protein coupled receptor kinase-2 (GRK-2).
We observed DBS-stimulus NMD predictions in genes participating in DNA damage and repair and alternative splicing, compatible with our findings of bidirectional risk-protection role of these pathways by meta-analysis of mouse PD model brain transcriptomes [ 48].
But here, the PWC takes a role of bidirectional wavevector coupling and phase matching.
The need to adapt education to the requirements of knowledge-based society has increased the role of bidirectional communication in classroom in order to obtain educational performance.
In conclusion, our systems biology modeling of bovine oocyte and cumulus proteomes, in the context of gene ontology and canonical protein interaction networks identified ninty-one proteins involved in the cell-to-cell signaling biological process that may have role in bidirectional communication between oocytes and cumulus cells.
Therefore, cold stress could modify levels of cytokines and immune responses, because cytokines play a crucial role in bidirectional communication between neuroendocrine and immune systems [ 48].
This hypothesis agrees with the increase in transcription levels of peptide transporters, which can play an important role in bidirectional transport of peptides.
HDL-C The anti-inflammatory effects of pitavastatin result in increased expression of macrophage scavenger receptor class B type 1, which plays an important role in bidirectional cholesterol interchange between cells and HDL-C [79].
