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Understanding of the concept of impaired functioning has changed from biomedical and social perspectives to the biopsychosocial model in the last decades [ 20], emphasizing the dynamic and bidirectional interrelationships between health conditions and contextual factors (personal and environmental) [ 21].
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The multidimensional nature of fatigue was well described by Hewlett et al. [ 13] in their conceptual model of the interaction between fatigue and three components - disease process, cognitive and behavior aspects, and personal life issues - with a bidirectional path suggesting interrelationships among these components.
Further research using longitudinal designs is needed in order to test the directional and bidirectional nature of the observed interrelationships.
The interrelationship between vitamin D status and adiposity is complex and possibly bidirectional.
This problem is bidirectional.
Without these, the melodrama pales but the human interrelationships intensify.
The interrelationships between different services needs to be considered.
I miss interrelationships with all kinds of people.
Palms are diverse and their interrelationships are not clear.
Interrelationships among labor markets.
bidirectional tunneling.
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CEO of Professional Science Editing for Scientists @ prosciediting.com