It was found that specific cis-motifs were over-represented in bidirectional promoters compared with unidirectional promoters (5), and that the co-regulation of bidirectional genes may involve different h2h pairs (7).
TAF1 and NELFe had ChIP-seq signals similar to that of RNA Pol II with higher signal upstream of the TSS of the bidirectional genes compared with the unidirectional ones.
The patterns for TAF1 and NELFe were very similar to the pattern for RNA Pol II with a higher peak upstream of the TSS in the bidirectional genes compared with the unidirectional ones.
In an earlier study [ 13] we observed that the histone 3 acetylation (H3ac) signal upstream from the transcription start sites (TSS) was lower in unidirectional compared with bidirectional genes whereas both groups had approximately equal signal downstream of the TSS.
Consequently, in order to exclude the contribution of chromatin-level gene regulation, the co-regulation level of bidirectional genes should be compared with other adjacent gene architectures as well as the random gene pairs.
The performance of the synthesized array is discussed and compared with the bidirectional linear SA.
As the DAB converter has many advantages, such as galvanic isolation, zero-voltage switching, high power density, high efficiency, and symmetric structure [6], it has been drawn more attention compared with other bidirectional DC-DC converters.
