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MTX (Sigma Aldrich, St Louis, MO, USA) dissolved in 7% sodium bicarbonate solution was given orally 3 times a week from the first day of immunization.
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Bicarbonate 8.4 or 4.2% solution was given intravenously as a buffer to the patients with metabolic acidosis.
We used 4.2% sodium bicarbonate solution as sole treatment in calves without clinically relevant dehydration, and 4.2% or 2.1% solution was given in dehydrated calves prior to the 5 liters of isotonic saline spiked with 250 ml of 8.4% sodium bicarbonate solution.
Normal saline and bicarbonate Ringer's solution were given.
The pH values of these solutions are given in Table 1 and range from 5.3 for ammonium sulfate, chloride, and bromide to 8.2 for ammonium bicarbonate.
In this study, the endothermic decomposition of ammonium bicarbonate solution was used to generate CO2.
Nevertheless, sodium bicarbonate solution was as effective as sodium chloride solution at regenerating MIEX resin.
Fifty microliters of 1 M sodium bicarbonate solution was added into a 0.5 mL of 100 μM BSA and LYZ solutions.
The resulting bicarbonate solution is then filtered to remove insoluble material.
One should note that mixing of the bicarbonate solution is often done at the bedside or in the hospital pharmacy, with the possibility for errors leading to the infusion of a hypertonic bicarbonate solution.
On admission, high-dose methotrexate (5.5 g/m×1 dose) was administered after 2 L of isotonic sodium bicarbonate solution were infused.
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