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A highly biased set of Boolean functions is observed in simulations of networks of various sizes, suggesting a new characterization of the subset of Boolean functions that are likely to appear in gene regulatory networks.
These arrays included a severely biased set of CpGs located in known cancer-associated genes and CpGs located almost exclusively in CpG island promoter regions, respectively.
Note that the detection of transcripts is not conditioned on a possibly biased set of probes nor on the resolution of the array.
Finally, data available from shotgun sequence, such as the reads we used, will reveal a much less biased set of var genes than those revealed by targeted PCR [ 5, 7].
Finally and most importantly, we may have included a biased set of large physiological cupping eyes, as eyes with additional anatomic features (such as violation of the ISNT rule) may have been more likely to be followed clinically for possible glaucoma than those with large physiological cupping but no other features.
On the contrary, a concern is that, owing to their opportunistic nature, many phase I or II studies would only be registered if they identify a significant finding, resulting in a biased set of registered phase I and II studies, akin to the problem of publication bias.
Similar(41)
This overlap in phosphorylation of a strongly mammalian-biased set of kinase substrates indicates that a subgroup of kinases is present in divergent eukaryotes has similar peptide sequence requirements for catalysing phosphorylation reactions.
We performed a Chi-square test to test the null hypothesis that the distribution of genes was unbiased, i.e., that gene constellations were represented in the male-biased set of genes as expected based on their abundances in the genome.
One possibility is that natural selection may have biased the set of proteins found in nature to favor only those structures that are well suited to the cellular environment.
According to the same logic, this could have biased our set of BRCA1 carriers towards those with a lower than average density.
This approach prevents a few outlier strains from dramatically biasing the set of core genes characteristic of a bacterial species.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com