Introducing some biasing into the library selection process does not interfere with the main purpose of this workflow, namely, the selection of libraries for phenotypic screening but rather increases the probability of identifying active hits.
Similarity to active compounds (if such are known) could be used to bias the selection of the screening library.
The main focus of the workflow is the selection of complete libraries for unbiased screening, namely screening which is not biased by knowledge of the structure of the biological target or of compounds known to interact with it.
GBS protocols could be optimized for polyploid species by varying factors affecting the evenness of sequencing across loci, such as PCR polymerase bias, size selection of fragments, and choice of enzymes used to generate the libraries.
Organizations bias their selection of stories to highlight the triumphs.
Due to its retrospective nature, the results of this study are subject to several forms of bias including selection bias, verification bias, test review bias, and incorporation bias.
This risk of bias tool covers six domains of bias: selection bias, performance bias, detection bias, attrition bias, reporting bias, and other bias.
Here we focus on two major categories of bias: selection bias and information bias.
The tool covers six domains of bias: selection bias, performance bias, attrition bias, reporting bias and other bias [ 13].
