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However, a spindle component is needed so that this imbalance can be transduced into a biased segregation.
For example, bands E1H10-076, E4H9-071 and E4H15-550 had significantly biased segregation in MD24ScPop population.
The biased segregation ratio of SUI phenotype in the mlpk/ mlpk background suggested an MLPK-dependent incompatibility system operates in the SUI reaction.
In addition, abnormal distribution of nucleoids was observed in the overexpresser and ~2% cells exhibited extremely biased segregation of nucleoids during cell division.
Centriole asymmetry is also important for the biased segregation of mRNAs and transcription factors., The mother centriole is responsible for cell geometry and relative positioning of other organelles within the cell.
Here, by using the budding yeast as a model for replicative aging, we identify an Hsp42-promoted and Hsp104/Hsp70-counteracted pathway that deposits age-associated protein aggregates and thereby ensures their biased segregation to the aging mother-lineage upon cell division (see model in Figure 7D).
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We believe that equational separation of univalents at anaphase I leaves open the possibility of biased (or random) segregation of single chromatids at anaphase II (this was already stated in our Introduction and is now stated in the Discussion).
Instead of exhibiting strongly biased and complete segregation to the PS block of PS- b-PMMA as seen for the globular proteins, Fg displays adsorption events more neutral to both blocks, involving not only PS but also PMMA phases at specific conditions.
For deposition temperatures near ∼ 500°C, and/or biased substrates, the complete segregation of phases was observed (no traces of phase 2), thus forming a nanocomposite structure composed of nanocrystalline grains of TiN embedded in an amorphous silicon nitride phase-nc-TiN/a-Si3N4.
It would require the combination of stable heteroplasmic mtDNAs containing different GC42 patterns, relatively efficient mtDNA recombination and segregation, and biased retention of high GC42-copy mtDNA genotypes.
Therefore, it is probable that the longer LGs observed within the male Clementine map do not result from biased estimations due to segregation distortion, but instead reflect differential recombination rates.
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