Sentence examples similar to biased screenings from inspiring English sources
Recently, new methodologies based on machine learning, in silico pharmacophore-based and in silico anchor-biased screenings, as well as stereoselective and one-pot chemical synthesis have led to rapidly increasing hit rates.
However, such relatively low-throughput screenings were biased towards abundantly or ubiquitously expressed miRNAs [ 6] and missed many miRNAs with restricted temporal or tissue-specific expression patterns [ 1].
Our estimated benefit may be slightly biased in favour of screening by the selection of recently diagnosed cases (1995 2004), which will of necessity be relatively rapidly fatal and therefore may under-represent screening-exposed fatal cancers.
Others have questioned the importance of lead-time bias in CRC-screening studies as well (Ransohoff and Lang, 1991).
Lastly and uniquely to this study, because the majority of the cohort (83.3%) had complete flexible sigmoidoscopy CRC screening at baseline, all participants had an equal opportunity to be screened, so any screening-related biases are unlikely to be a factor in this study.
Sensitivity for the initial screenings was affected by length bias and overestimation because lung cancers with long preclinical detectable phases were more prevalent.
As both incidence and mortality are decreasing since the early 2000s in Germany (Husmann et al, 2010), it is unlikely that observed trends in population survival could be fully explained by screening-associated biases.
Overdiagnosis bias refers to the screening-related detection of cancers that would not have contributed to the death of the patient because of competing causes of death or because the lesion is indolent.
Population-wide echocardiographic screenings may be subject to length time bias or pseudodisease, and the children diagnosed are likely to be among the majority of ARF patients in whom carditis resolves within a year of initial attack.
