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The biases listed above also operate in the workplace between employees and supervisors.
To further account for recall bias, lists of possible services were presented (e.g., every outpatient service was addressed specifically in the questionnaire).
It is well known that there is a real logistical difficulty that consists in combating at least one of the potential biases listed above.
Combining with the protocol of the Two-Cycle Labeling Assay (Affymetrix, Santa Clara, CA, USA), we postulated that there may be three possible reasons for the bias listed as follows.
Some major risks of bias listed in Cochrane reviews (adequacy of randomisation, concealment of treatment allocation, blinding of the outcome assessor, ITT-analysis) [ 10] were present in the majority of studies.
In homage to these geographic origins, Krathen has curated a hundred-and-fifty-bottle list biased toward Piedmontese varietals.
We believe we are reading the best work that the publishers have to offer, not a list biased by contractual obligations.
However, the high percentage of DAE that we observe in out study is likely to be biased by our list of candidate genes, and will not necessarily correspond to the percentage of DAE genome-wide for any of the tissues we studied.
Although Tarbase does not represent a non-biased list of microRNA targets, it is interesting to compare our list of 2+DB microRNA interactions to those present in their database.
The LW-biased list comprised genes involved in ATP biosynthetic process, nervous system development, lipid metabolism, RNA processing, and control of growing and cellular division.
Furthermore, the PicTar and TargetScan lists are more similar to each other than to the miRanda list, and so the combined list is biased toward the genes predicted by these algorithms [Additional file 3].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com