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The initial attractor S has variation in many directions in the state space, and involves a larger number of expressed genes, whereas differentiated cells A or B have biased expressions represented by lower-dimensional attractors.
Types A1 and A2 have further biased expressions.
This supports previous observations that male-enriched genes have biased expressions than female-enriched genes in zebrafish [ 42], fly [ 43] and C. elegans[ 44].
The biased expressions are estimates over the real terms in the summations of expressions 8, 9, and 10.
To infer system-level emergent complexity, we re-investigated the same data without any biased expressions cut-off.
However, the differential expressions identified between embryonic stages were both reliable (minor intersect with biased expressions) and relevant (biologically validated).
Similar(54)
Our first observation was that all nuclearly encoded duplicates having biased expression are testis-biased (i.e., we did not find any gene having biased expression for any other tissue; supplementary table 3, Supplementary Material online).
We detected parent-of-origin (PO) biased expression of 48 genes, an equal number of which were expressed with maternal and paternal biases, respectively.
The majority of genes showing gender biased expression either in diseased human and murine kidneys were different from those differentially expressed in healthy kidneys.
In our opinion this is risky because on the other hand biased expression values with many unreliable quantities are used.
Recombinant His6-TEV-FXRs were expressed in a SGC-generated derivative strain of BL21 Escherichia coli with the pRARE plasmid for codon biased expression.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com