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As they discussed, some important limitations of their studies have to be noted: retrospective study, selection bias of samples, the availability of suitable tissue and absence of a set of nonmalignant control samples, all affected miRNA expression differences.
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According to our pathway-associated differential significance analysis, we found keratin associated pathway were significantly overall bias with diabetic serum, which might not result from the bias of sample preparation.
To avoid the bias of sampling from the mouse genome, we searched each motif on the whole genome.
It is thus possible to argue that the bias of sampled proteomes per superkingdom can cause long-branch attraction, which can eventually lead to incorrect deep phylogenetic relationships.
The exchange bias properties of samples were investigated by measuring field cooled (FC) hysteresis loops in the temperature range 5-300 K.
In the current study, each of the samples was individually analyzed using bTEFAP [20], which enabled us to remove the bias of pooling samples.
Our sample was recruited from a PHCC, and although it is a healthcare setting, our results showed the optimistic bias of the samples from the community.
Apart from selection bias of study samples, there seems to be a systematically difference when comparing volume data using VBM or the region of interest (ROI) method.
A source for climate data was lacking, selection bias of serum samples likely and no co-factors were included (Grade 2).
Alternatively, changes in allele frequencies between pre and post-epidemic samples in the Lossi population could stem from other survival bias which led to a bias composition of sampled individuals in the post-epidemic sample.
This might result in a systematic bias of the sample.
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CEO of Professional Science Editing for Scientists @ prosciediting.com