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On the other hand, the survival advantage likely also stems from the inherent selection bias in a retrospective cohort.
The early complication rate is prone to information bias in a retrospective study, but our report of 36.3% with ≥ 1 complication was within the same range as in previous reports [ 4, 7, 12, 13].
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This may have been due to bias inherent in a retrospective study.
Although variation in patient management over time, particularly in multicenter studies, is a potential bias in any retrospective study, this effect is minimal in this report since the same breast oncology team treated patients in the recent years.
Second, this is a selection bias in a multicentre retrospective study.
One is the inherent bias in all retrospective studies of archival tissue which may be lessened in this study by the high sample collection rate.
Though expensive and time-consuming, establishing large cohorts is still preferred to avoid the impact of these biases introduced in a retrospective study that cannot be fully controlled by any analytical method.
This selection bias is unavoidable in a retrospective study, but may be limited.
Despite a good accuracy, we must point out that historical inaccuracies and biases are unavoidable in a retrospective database analysis, and the figures drawn from it must be taken cautiously.
First, the findings from the clinical correlation are preliminary in nature due to the relatively small sample size and inherent biases in any retrospective study.
Because of the possible bias in this retrospective study, a BI-RADS classification [ 20] could not be scored objectively and was therefore not included in the evaluation.
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