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A further explanation could be that obesity makes prostate cancer identification more difficult, thus predisposing obese men to present later with more severe disease, but reducing the identification of low-grade, low volume disease (detection bias, generating positive association with advanced cancer but inverse associations with localised disease).
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GC content and evenness GC distribution in the chromosomes are important factors influencing the bias generated by PCR based processes.
Despite of a slight bias generated during NSR hexamer priming, the NSR-seq method still robustly reproduces the same transcript sites in different samples.
The RPKM of the 92 Spike-In transcripts was then used to obtain an overall estimate of the bias generated in the NSR priming in the directional cDNA synthesis, PCR amplification and sequencing.
Rosenbaum and Rubin showed that under the assumption of strongly ignorable treatment assignment, given the observed covariates, selection bias generated by the differences in observed covariate values between the two groups can be removed [4].
Prestige bias generates temporal (but not spatial) mass suicide clusters.
Similarity bias generates temporal (but not spatial) mass suicide clusters.
Hypothesis 2b, that similarity bias generates temporal (mass) suicide clusters, is therefore not supported.
Note that this standardization accounts for the bias generated by conditioning each window to start with a SNP.
Hence a trend towards elevation of serum eotaxin in CRs could be an effect of Th2 bias generated by IFNβ treatment.
The appearance of the bias generated by multifunctionality could be completely removed by artificially forcing all genes to have the same node degree.
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