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Due to their equal abundance, using a peptide from a single histone for normalization of all measured histone PTMs should generate similar quantification results and relative standard deviation (RSD) without a bias for using the respective histone that contains the PTM for normalization.
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The MSE naturally penalizes for bias (from using a training set smaller than n) and variance.
Two alternative approaches have been developed to handle bias: adjusting for bias using a statistical model and filtering regions of the genome suspected of harboring bias.
The observed significant bias for use of one option over the other with the flip-top task implies that the actions of demonstrating individuals drew the attention of conspecifics to a specific option, causing them to direct the majority of their manipulations towards it.
To create a standard fractional anisotropy template with minimal bias for use in the voxel-based analysis we adopted an iterative procedure with three stages.
Generally, bias for use the left hand is more characteristic of males, whereas a greater right-hand use has been noted for females (e.g., [ 8, 48, 50, 52, 53]); although a number of primate studies failed to reveal any differences in motor laterality between the sexes [ 54- 60].
Since atypical antipsychotics differ in their metabolic side-effect profile, there could be a channeling bias for use of specific atypical antipsychotics based on the presence of these conditions at baseline, thus resulting in the need to control for these specific covariates.
That leaves a skewed impression of the evidence.Researchers have been studying publication bias for years, using various statistical tests.
They also accused Western media of bias for not using the word "terrorist".
We found minimal evidence of publication bias for pneumonia using standard methodologies.
However, such bias can be controlled for using various statistical techniques such as multiple regression analysis [37].
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