Sentence examples for bezafibrate on the development from inspiring English sources
Our data, derived from patients with coronary artery disease, support the hypothesis regarding a possible preventive effect of bezafibrate on the development of colon cancer.
We therefore sought to investigate a potential preventive effect of bezafibrate on the development of colon cancer in patients with coronary artery disease enrolled in the randomized, double blind Bezafibrate Infarction Prevention BIPP) Study.
The main novel finding in this post hoc analysis of the BIP study, which was randomized and double blind in design, is a possible preventive effect of bezafibrate on the development of colon cancer in humans.
Therefore, we proposed to investigate a possible preventive effect of bezafibrate on the development of colon cancer in patients with coronary artery disease during a 6-year follow-up.
The suppressive effects of nimesulide, troglitazone and bezafibrate on the development of colonic adenocarcinoma was well correlated with the inhibition of cell proliferation activity, induction of apoptosis, and lowered immunoreactivity of β-catenin, COX-2, iNOS, and nitrotyrosine in the colonic malignancies.
Further, Tenenbaum et al. reported that bezafibrate decreased the development and delayed the onset of type 2 diabetes in patients with impaired fasting glucose [ 38].
Dietary administration of nimesulide, troglitazone and bezafibrate effectively suppressed the development of colonic epithelial malignancy induced by AOM/DSS in female ICR mice.
However, the effect of bezafibrate on colon cancer development in humans is unknown.
