Sentence examples for beyond the upper normal from inspiring English sources
In both groups, renal function parameters showed an increase in creatinine and urea during treatment with L-AmB, but not significantly beyond the upper normal limit.
Laboratory parameters of hepatic function showed a statistically significant, yet transient increase in ALT and AST in both groups, beyond the upper normal limit during treatment post-transplant in relation to baseline (P < 0.001) as well as to day 0 (P < 0.001).
Patients were excluded from the study if at baseline: (1) their central vision was deteriorated beyond 20/100 visual acuity; or (2) they had abnormal liver function tests, defined by increase in liver aminotransferases, alkaline phosphatase, and serum bilirubin levels beyond the upper normal limit.
The blood analysis of liver and kidney parameters showed a significant increase beyond the upper normal limit of ALT between baseline and maximum in all three groups, i.e., fluconazole (p = 0.031), itraconazole (p = 0.015), and posaconazole (p = 0.007), and a significant increase of AST between baseline and maximum in the fluconazole (p = 0.049) and posaconazole groups (p = 0.005) (Fig. 1).
The upper normal limit for LDH is 240 U l−1.
Severe liver insufficiency (the serum alanine aminotransferase or aspartate aminotransferase level is threefold beyond the upper limit of normal (ie, >120 U/L); or the total bilirubin level is threefold beyond the upper limit of normal (ie >60 μmol/L)).
Concomitant renal insufficiency (serum creatine level is 1.5-fold beyond the upper limit of normal (ie, >170 μmol/L)).
Therefore the absolute upper normal threshold may vary between trials.
Kidney parameters creatinine and urea were not significantly elevated beyond the upper limit of the normal range during antifungal monoprophylaxis in any of the treatment groups (Fig. 2).
Mean LS based on BMI ANOVAA p < 0.0001; Figure 2) and the proportion of those with LS beyond the normal upper limit (x2 = 14.31, p = 0.0008) also significantly differed among the three groups.
