This will eventually result in other conformational changes that are beyond the timescales of the simulations performed but that would lead to the misfolding and aggregation of PFN1.
Over the same period, major discoveries in Asia and Europe have similarly expanded our knowledge of early occupation of those regions and have led to a dramatic lengthening of the timescale since hominids expanded beyond the tropics.
A deeper understanding of the timescale of daphniid evolution has implications beyond biogeography and systematics.
"Achieving the water quality targets in the timescale proposed is likely to be well beyond the funds currently allocated by the Queensland and Australian governments".
It's up to them to decide on the timescale".
We were surprised by the timescale of weeks," added Jones.
Set realistic expectations for the timescale for delivery.
Disagreements are basically about the timescale -- the rate of travel, not the direction of travel.
The vast majority of people are incapable of significant understanding or planning beyond the personal timescale; indeed, there is little evolutionary reason for human minds to function in timescales longer than this.
"Its stay in Sheffield was always a temporary arrangement which has been extended beyond the original timescale of six months and we appreciate and accept its owner's decision to move it to a new location so it can be in place for Christmas.
Yet, some restrictions on paxillin-YFP diffusion are likely to exist (see Discussion), since free cytoplasmic GFP (Figure 1C) exhibited even faster recovery (beyond the experimental timescale).
