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Also, commissioners expected some outcomes to be achieved beyond the time scale of our study.
At the same time the present investigation shows the advantages but also limitations of TMD simulations in which large conformational motions, usually beyond the time scale accessible by MD simulations, are enforced on a time scale of several tenths of nanoseconds.
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As a result, there is an emerging need to characterize the disease beyond the time scales used in conventional protocols.
In this he expanded the time scale considerably beyond the accepted "Mosaic" chronology of less than 10,000 years from the beginning of the world to the present, to an estimate of approximately 75,000 years in the published version, and over two million years in his draft manuscript.
In this paper, we will apply the steered molecular dynamics (SMD) simulations to study the dissociation behaviors of inhibitors under external force considering that the time scale of dissociation processes is beyond the limit of classical MD simulations.
Since the time scale of the open to closed isomerization process is beyond the limit of current time-dependent MD simulations, a series of intermediate conformations were generated using the time-independent partial nudged elastic band (PNEB) method.
Then there is the time scale.
This work contributes clear evidence, in a simple setting, that noise-driven transitions among stable, asynchronous collective network states constitute a viable and robust mechanism for spanning 'behavioral times' far beyond all the time scales of the neural and synaptic dynamics.
Accurately dating viral evolutionary events can therefore be a complex and sometimes controversial task especially when it requires the extrapolation of evolutionary rates either beyond the time-scales over which they are valid or to virus genotypes or species that are only distantly related to those for which the rates were inferred.
Improvement in maternal education and reduction of infant morbidity as a result of our intervention may yield long-term benefits beyond the time-scale of the trial.
Direct simulation of permeation of ions or molecules through a gap junction channel is beyond the current computational power due to the time scales involved (of the order of τExp, i.e. a few ms).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com