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Some studies fit models to empirical data from extended lactation records [ 14], whilst others use fitted models to predict the potential for extended lactation in the absence of actual data records beyond the reference date.
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This reference point will hereafter be referred to as the reference date.
The reference date for the interview, a date beyond which exposure information was not collected, was the month and year of diagnosis for cases and a randomly assigned date for controls.
The reference date for WHI is the baseline questionnaire date.
Age was calculated as of the reference date.
Exposures after the reference date were not considered.
Note: Baseline questionnaire completion is the reference date.
The date of the mammogram was the reference date used for all exposure definitions.
For the cohort with diabetes, the date of diabetes onset was considered the reference date.
The reference date for risk-tested patients was the date of blood draw for the test.
The reference date for controls was set to the date of diagnosis of the matched case.
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