Patient-oriented and epidemiologic research projects, particularly multicenter projects, typically generate data with potential utility beyond the specific hypotheses and questions for which they were designed.
Thus, the presence of plaques cannot predict with any accuracy or specificity that an individual is going to acquire the disease — and researchers are increasingly looking beyond the amyloid hypothesis for an adequate explanation for Alzheimer's.
In accordance with her view that Locke's agnostic tendencies (just like his dogmatic ones) are genuine, Wilson interprets Locke's concept of superaddition robustly, as a sort of divine action that goes beyond the corpuscular hypothesis.
Answers are only ever as good as questions, and thoughtful and honest analysis of data must look beyond the study hypothesis to what actually happened.
This high-density array is also anticipated to take research beyond the classical hypothesis of additivity of QTL effects or of QTL and environmental effects.
The recent surge of novel findings moves beyond the channelopathy hypothesis, implicating pathways that regulate synaptic vesicle trafficking, mTOR signaling, chromatin remodeling and transcriptional regulation, which offer new insights into disease-causing mechanisms and provide novel avenues for therapeutics.
Two years later, Ingram and colleagues [ 31], who clearly identified the need to go beyond the cholinergic hypothesis to establish other animal models that would help answer questions pertaining to AD not strictly related to cholinergic neurotransmission, advocated the use of such models.
Beyond the previous analysis, the hypothesis of an overestimation of the risk is supported by the temporal pattern of drug purchases and by sporadic self-imposed school closures.
The hypothesis beyond the development of this index was to improve BC grading and its prognostic value.
