Sentence examples for beyond the active site from inspiring English sources

Thirteen sites are revealed, expanding possible target sites for ligand binding well beyond the active site.

Extending beyond the active site, new observation suggests that catalysts can effect reactions to proceed at distances away from the active sites.

Ginovska-Pangovska, B., Dutta, A., Reback, M. L., Linehan, J. C. & Shaw, W. J. Beyond the active site: the impact of the outer coordination sphere on electrocatalysts for hydrogen production and oxidation.

Evidence for specific binding extending beyond the active site has been obtained from crystallographic analyses of several RNase A-nucleotide complexes viz d(CpA) [18], ApC [19], pTp [20], and other studies including NMR [21], [22].

The crystal structure of a d(ApTpApApG .RNase A complex solved by X-ray diffraction shows the existence of a specific substrate recognition region on RNase A that extends beyond the active site [23].

Other mutations (V10, W30 and I94) beyond the active site have also been identified in clinically isolated TMP-resistant genes [ 46].

The molecular docking results indicated that the inhibition mechanism was different between the two families due to their different structural characteristics beyond the active sites.

If possible, k cat should be measured with less error (e.g., using alternative substrates), in order to eliminate the possibility that phosphorylation affects turnover rate as well as binding constants, which would indicate mechanisms beyond simple steric interference with the active site.

If possible, kcat should be measured with less error (e.g., using alternative substrates), in order to eliminate the possibility that phosphorylation affects turnover rate as well as binding constants, which would indicate mechanisms beyond simple steric interference with the active site.

The two additional well-ordered K+ ions, one of which shares a bridging phosphodiester oxygen ligand with the nucleophile-coordinating Mg2+ ion, would impart additional electrostatic modulation at the active site beyond the roles of the Mg2+.

The role of the N-terminal domain would appear important not as a mere structural extension of the active site beyond what is seen in other lytic transglycosylases but one that creates a peptide-binding site at position +2.