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This defined three groups – 1) "limited disease" (a tumour confined to the primary site with or without local lymph node involvement), 2) "extensive disease" (any indication of disease spread beyond local boundaries) and 3) "unknown" (not recorded or not known).
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Doctors, whose relationships tend to be at the local level and not beyond their local boundaries unless they are attending seminars and symposia, are also acutely aware that knowledge in their field is constantly developing and sometimes at a rapid pace.
One is the birth of the World Headache Alliance, bringing together many lay organisations worldwide into cooperative actions, pursuing objectives that go way beyond the national or local boundaries of each.
It presents a wide variety of current research and approaches the field of international labor migration from a regional perspective, acknowledging that the migration process goes beyond local and national boundaries and is embedded in regional and global interconnections.
The potential for high diffusion rates increase when the product is highly transportable, bringing distances way beyond local and regional boundaries within reach something that depends on the product characteristics, transportation costs and the availability of the infrastructures needed.
Straighter movements resulted in deposition farther beyond the local habitat boundary with lower impact than more sinuous movements.
Some are beyond local control.
Later, as the tribe grew rich on casino profits, it began to add land beyond even those boundaries, which led to extensive court battles over whether it could annex nonreservation land and put it into "trust status," where the federal government holds title to the property, which puts it beyond local rules.
But the dynamics of change went beyond local authorities.
Images courtesy of Beyond All Boundaries, used with permission.
New regional adoption agencies work across local authority boundaries.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com