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These studies demonstrate the distinct roles of White in various types of behavioral plasticity and anesthesia beyond its function in the eye.
Yet the role of XBP1 in plasma cells was proposed to extend beyond its function in the UPR.
Thus, Ghaziani et al [ 36] suggested that HO-1 importance extends beyond its function in the catabolism of heme.
Taken together, these findings support an important biological role for glycogen metabolism in the brain beyond its function in glucose homoeostasis.
Beyond its function in cell migration, Bcl-wav was found to act as a pro-apoptotic Bcl-2 member inducing Bax/Bak dependent cell death.
This analysis further revealed that at some demethylated loci, paternal methylation in TET3 zygotes actually increased to higher levels than in sperm (i.e., value > 1 on Figure 3D), implying that beyond its function in demethylation, TET3 is required to protect certain sequences from aberrant de novo methylation in the zygote.
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Hence, the indication for its use in septic patients was abandoned, beyond its function to provide renal support in the presence of renal dysfunction [ 11].
We conclude that R2D2 functions beyond its role in RNA interference to include ovarian development in Drosophila.
Accumulating evidence indicates that TERT may have additional functions, beyond its role in preserving telomere homeostasis.
Although caspase-8 is a well-established initiator of apoptosis and suppressor of necroptosis, recent evidence suggests that this enzyme maintains functions beyond its role in cell death.
As TNKS, the primary drug target of JW74, is implicated in cellular functions beyond its role in the DC, such as telomere maintenance, glucose metabolism, and centrosome maturation 45, the observed effects may not be exclusively explained by altered β-catenin levels.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com