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Silencing of BECLIN1/ATG6, ATG3, or APG7 resulted in the spread of cell death, suggesting that autophagy plays an anti-death role during pathogen infection to limit the spread of HR beyond initially infected cells [ 52].
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Markets in Europe and beyond responded initially with predictable nervousness to the news from Italy.
AD helps to conceive controllable and manageable designs, beyond fulfilling initially posed requirements.
Implementation of new interventions among communities must factor in the possibilities of transformation and/or emergence of new innovations beyond those initially conceptualised as implementation progresses.
However, the scope of the United States' de-Baathification efforts would soon expand well beyond that initially limited scope The U.S.-led Coalition Provisional Authority CPAA) ultimately required a governmental purge of all Baath party members, although there were exemptions provided to certain local coalitions.
He successfully managed the forced migration of users off Facebook's chat feature to Messenger, laid the foundation for advertising and business tools and turned the app into a platform for games and useful utilities (beyond the initially half-baked bots).
Their movement became more radical, going beyond the initially purely fiscal demands.
CO suppression of numerous chemokines beyond those initially described indicates an ability of CO to broadly modulate chemotaxis and cell recruitment, early events in establishing a local inflammatory response.
As suggested by the reviewers, we also increased the dose of erlotinib beyond that initially tested.
These results encouraged evaluation of ESAs in clinical studies in a wider range of indications, beyond those initially approved.
Informed consent forms explicitly state that samples will only be kept until analysis and no use beyond that initially predicted and informed to the donor will be made.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com