Sentence examples for between visceral hypersensitivity and from inspiring English sources
Previous studies have reported that the severity of IBS symptoms was positively, although weakly correlated to altered rectal perception [ 18, 19] and to alteration of pain processes [ 16]; others failed to find a significant correlation between visceral hypersensitivity and most IBS symptom severity [ 20], although, many of these studies were limited by the use of non-validated questionnaires.
In contrast Hong et al suggested that no difference exists between visceral hypersensitivity in patients with NERD and those with erosive esophagitis [ 23].
Visceral hypersensitivity and altered pain perception also appear to be important features of IBS, as demonstrated in rectal sensitivity experiments.
In adults with IBS, increased intestinal permeability correlates with increased visceral hypersensitivity and abdominal pain symptoms [36].
To test the hypothesis that abdominal pain related to functional gastrointestinal disorders is associated with visceral hypersensitivity and abnormal perception of visceral sensations.
Separation of newborn rats from their mothers induces visceral hypersensitivity and impaired epithelial secretory cell lineages when they are adults.
In addition, they underwent hydrogen breath testing to identify lactose malabsorption, rectal barostat testing to measure visceral hypersensitivity, and ileocolonic biopsies to assess neuroimmune activation.
In a randomized, parallel, controlled trial in adults with IBS, ketotifen (a mast cell stabilizer) both decreased visceral hypersensitivity and improved intestinal symptoms [46].
Widespread visceral hypersensitivity and the overlap of symptom complexes observed in functional gastrointestinal disorders may be related to central sensitization and neuroplastic changes.
These data suggest that the action of NGF on sensory neurons contributes to the development of visceral hypersensitivity and that anti-NGF strategy may be of some therapeutic benefits in digestive sensory disorders.
The precise molecular pathophysiology remains to be elucidated but altered visceral perception (visceral hypersensitivity) and gut dysmotility are important contributors to symptom progression [3], [4].
