The autocorrelation between two time points and is mathematically defined as (1).
A time-dependent effect between two time points was classified as statistically signification if the P-value is < .05.05
This may have occurred since the difference of patient positioning in particular cases could be large, resulting in large deformation during registration between two time points.
Ovals indicate the number of differentially regulated transcripts between two time points; circles indicate the number of differentially regulated transcripts shared between all time points.
For a signal with maximum amplitude c, the interval between two time points T k = tk+1- t k satisfies: (2).
Since the sample size in each time point was not equal, Mann-Whitney test was used to compare cytokine responses between two time points of measurement.
Heat-maps consist of explicit representations of concentration ratios between two time points, where metabolites (row) and samples (columns) are reordered in an unsupervised fashion.
We introduced a dynamic parameter, e.g. regulation between two time points, which obviously eliminates genes that are constantly expressed by the endothelium.
Statistical significance of comparisons between H37Ra and H37Rv or between two time points was determined using a two-tailed, unpaired Student's t test.
Difference scores or calculating the difference between two time points to give one statistical value per rat, were also used to decompose interactions for ethanol and other drug conditions throughout the study.
Fold changes were computed from the median ratio of original concentrations between two time points and are presented as changes compared to the control group (positive values) or to the treated group (negative values).
