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STRING PPI datasets (version 9.0) is used in the distance calculation between two pathways in the current version of IntPath (V2.0).
We define an interaction function to evaluate the significance of all non-empty overlaps between two pathways in different brain regions individually, i.e., where P i and P j are two pathways, and O ij is their overlapping.
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Accumulating evidences suggest that a cross-talk between two pathways exists in cells as the active caspase-8 cleaves a BH3-domain-only subfamily protein, Bid.
The number of edges in each interaction network that have a weight smaller than the maximum path length (see methods) and hence may contribute to a path between two pathways is shown in Table 1.
Herein we provide novel evidence of a link between two pathways that are overexpressed in breast cancer.
In the range of temperatures studied, an isopropanol to propylene mole fraction ratio close to 0.25 suggests a branching ratio of 1.5 between these two pathways in favor of propylene production.
We observed differences between the two pathways in the controlled case for sub-complexes like Cdc20 C-Mad2 and MCC (Figure 3).
Thus, a distinction between the two pathways in the controlled case is not possible based on our theoretical results.
Our results from exogenous application of WIN, which produces a smaller inhibitory effect on EPSCs at the PP than that at the SC, and from immunostaining, which shows a lower expression of the CB1R in SLM than that in SR, suggest that there is difference in functional expression of the CB1R between the two pathways in the CA1 region [33], [44].
However, cross-talk between these two pathways in biosynthesis of some terpenes was also recognised [ 44– 44].
However, by focusing on a single pathway these studies missed the interaction between the two pathways in this regulation.
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