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In this visualization (e.g. Fig. 3), the outer ring is the genome, the inner ring represents the genes (blue and orange representing genes on the forward and reverse strand, respectively) and the ribbons between two loci represent a conserved cluster.
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Nine loci represent coding sequences, and 21 loci are probable pseudogenes.
The patterns of bagging observed on both chromosome II and IV indicates that these do not represent simple interactions between two loci.
The r parameter represents the correlation between two loci and is preferred in association studies since an inverse relationship exists between r and the size of the sample needed for the same detection power.
The Kosambi mapping function (Kosambi 1943) was applied to determine the distance between two loci.
This has led to the recent development of statistical methods for detecting statistical interactions between two loci.
Equally, the two miR828 loci represented in Figure 4A-B likely represents paralogs and have highly similar hairpin sequences.
Seven separate loci representing potential members of this family on chromosome 7 (GenBank: NC_000073) were identified.
These novel loci represent variants that may be shared between these populations.
Two of these loci represented potential new precursors for already known miRNAs.
Each of the resulting ten, 21 locus (representing each chromosome) data sets was analyzed in IMa2.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com