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A molecular link exists between two key regulators of the "undifferentiated" state of proliferative cells.
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Snf1 and Mig1 in yeast are two key regulators involved in carbon catabolite repression [17].
We found that myostatin affects the protein levels of HK II and VDAC1, two key regulators of glucose metabolisms.
For example, the transcription factors OxyR and the SoxRS have been identified as two key regulators defending ROS effects.
Through analyzing two key regulators of G2/M arrest, namely cyclin B1 and phospho-Histone 3 (pH3), we confirmed the FACS analysis.
Four key regulators of development containing the homeobox sequences were identified as regulated by zinc deficiency.
By E7.25, approximately 30 40 founder PGCs are established following expression of the three key regulators: Prdm1 (BLIMPrdm14rdm14 and Tcfap2c (AP2γ) [ 1 3].
In this study, we genetically modified three key regulators to redesign the regulatory network of the expression of cellulolytic enzymes.
For these three key regulators, TFBS models are available for searches by Mapper [ 1, 2] and Genomatix [ 3].
Because we only performed the first-step targets enrichment in KEGG pathways, miR-204 was not among the six key regulators whose targets showed pathway enrichment, yet it was one of the heading regulators of 17 key regulatory modules.
LKB1 is one of two key upstream regulators of classical AMPK complexes in mammalian cells.
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