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For this model, we study how genotypes are arranged in genotype space, where the distance between two genotypes reflects the number of regulatory mutations that set those genotypes apart.
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As the distribution but not the number of DCX+ cells was altered in the mutant CA1, we concluded that the difference in the number of CamKIIα+ cells between the two genotypes reflects an ectopic localization of this cell population rather than a change in proliferation/differentiation.
Comparison between two genotypes was made by one-way ANOVA.
In a genotype space, the distance between two genotypes indicates the number of mutations that set those genotypes apart.
Between six and twelve genotypes were comparatively analyzed per marker.
A small Euclidean distance between two individuals reflects a strong similarity in state between their genotypes.
This variation was driven by a comparatively large fitness cost in two of the unevolved RifR genotypes, reflecting negative pairwise epistasis between the plasmid and D516G and I572S (Additional file 2: Table S2).
The highly significant interaction between growing season and genotype reflects differential responses of the four genotypes to different glasshouse environmental conditions across the three seasons, in particular the summer experiment in which the plants were subjected to additional heat stress (Fig. 2; Supplementary Data Table S1a; F6,39 = 56·17, P < 0·001).
The patterns of divergence among E. paniculata genotypes reflect relationships previously reported (see figure three [ 18]).
Hence, random changes in ancestral genotypes reflect on descendant phenotypes.
These results reflect the differences in leaf size between these two genotypes as would be expected.
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