Two discrete sample pieces replace a continuous sample for each of these regimes such that the total thickness of the discrete samples is identical with the thickness of the continuous sample.
Good correlation was found between POP-IF Ki values and a standard marker of proliferation, Ki-67: using seven discrete samples (POP-IF7, R2 = 0.81), using five discrete samples (POP-IF5, R2 = 0.80), using three discrete samples (POP-IF3, R2 = 0.64) and using three discrete samples without metabolite correction (POP-IF3M, R2 = 0.60, not shown), versus R2 = 0.85 for FA-IF as shown in Figure 4.
High correlation (Figure 3) was found between Ki values obtained by the full arterial sampling, and Ki obtained using the population-based input with seven discrete samples (POP-IF7, R2 = 0.98), five discrete samples (POP-IF5, R2 = 0.96), three discrete samples (POP-IF3, R2 = 0.88) and three discrete sample without metabolite correction (POP-IF3M, R2 = 0.85).
Comparison of subject 1 input function obtained using full arterial sampling (black curve) and average POP-IF (red curve) obtained using a) seven discrete samples up to 65 min (POP-IF7), b) five discrete samples (POP-IF5) and c) three discrete samples (POP-IF3).
Individuals are assumed to take the interval between two discrete dates as their time horizon.
When we speak of radicalism and religion, we need to distinguish between two discrete subjects: radicalism and religion, and religious radicalism.
A bistable system is one that toggles between two discrete, alternative stable steady states, in contrast to a monostable system.
The KL discrepancy is an information theory-based metric, measuring relative entropy between two discrete probability distributions.
Associations between two discrete variables were analyzed using the Fisher exact test.
The simplest models of ion channel gating are binary and alternate between two discrete permeation states: open and closed.
