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If no fiber exists between two ROIs, a zero weight is assigned to the corresponding edge.
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In practice, we represented the functional connectivity of the two brains altogether in the same graph: a link in the graph can be either an intra-brain or an inter-brain connection, according to the fact that it expresses the relationship between two ROIs belonging to the same brain, or between a region of one brain and a region of the other brain.
A weighted link between two ROIs indicates the degree of their interaction as estimated by the PDC.
This index of structural connectivity (mean radius) reflects thickness of a single fiber bundle between two ROIs.
The weight of the edge between each pair of nodes is defined as the density of the fibers connecting the pair, which is the number of tracks between two ROIs divided by the mean volume of two ROIs [49].
The middle panel demonstrates the generation of letter sequences used to describe each participants' search behaviour and the substitution matrix that provides information on the relationship between two ROIs.
The distance between two ROIs was obtained using the formula (x2+y2+z2)1/2 µm.
Since the distance between two ROIs was 1.8304 cm, the averaged apparent propagation velocity was calculated to be 2.96 ± 1.02 mm/s.
A cross-subject correlation at P = 0.001 two-tailed was treated as a significant connection between two ROI since the mean significance of the correlations between homologues in the term control data was 0.002.
In contrast, in the original data set, if a path of maximal diffusion exists between the two ROIs, most of the fibers constituting the corresponding edge should roughly have the same trajectory, and therefore have the same length.
From the time-activity plot for each ROI (Fig. 3a) the time of arrival (TOA) of the C-photoassimilate was estimated (see methods) [ 26], to calculate transport speed as distance between the two ROIs divided by the time of C transport between the two ROIs.
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Justyna Jupowicz-Kozak
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