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There were many more DEGs between gingers rhizome tissues and fibrous root tissue (MG versus FR and YG versus FR) than there were between tissues from the different parts of ginger rhizomes (MG versus YG).
Telomere lengths in different tissues are significantly correlated, with far less variation between tissues from the same individual compared to variation between individuals of a particular tissue type [18], [20], [21], [46] [48].
We next used the profiling method to detect methylation differences between tissues from the same individual.
Our study remains unique in its focus on comparison between tissues from the same individual.
Specifically, inadvertent DNA contamination or sample mixing would yield mosaic variation that could be erroneously interpreted as real mutation differences (instabilities) between tissues from the same individual.
Here, we employ a methylation profiling technique and a tiling microarray for human chromosome 1 to detect regional differences in the methylation state between tissues from the same individual.
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Sasai's lab-grown pituitaries form from interactions between tissues from two distinct regions of the embryo; their meeting causes part of the ectoderm to fold in on itself and detach, making a small pouch.
We found significant levels of interference caused by factors present in the extracts, which varied considerably between tissues (from a 2 10-fold underestimate of the Ins P6 added), and we attribute this to endogenous ATP diluting our [γ-P]ATP, plus other unknown compounds inhibiting the enzyme.
However, there were some variations between tissues from different patients especially in the number of viable cells isolated per gram of tissue.
This analysis aimed to identify genes that change in expression level between tissues from large datasets.
There are no differences in collagen expression between tissues from healthy individuals and normal tissues from affected individuals.
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