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A statistical association was found for the interaction between tissue type and risk group (p = 0.0623).
The model did not show any interaction between tissue type and risk group.
Also, these same positions vary little in methylation status between tissue type and through aging and are located in highly conserved, invariate regions of the genome.
In order to examine interaction between "tissue type" and "sample storage", we also entered the cross-product term "tissue type" × "sample storage" in the 3-way ANOVA model.
The significance of association between tissue type and GO category was calculated using Fisher's exact test assessing the accumulation of over-expressed genes in a tested category.
Unsupervised clustering of the 1% most variable CpGs (excluding probes that map to sex chromosomes or with known SNPs at the target site; termed XYS probes) revealed clear separation of samples into tissue-related groups, confirming the significant association between tissue type and methylation.
Similar(54)
Differences in inflammatory cell infiltrate between tissue types and in relation to adenoma size was assessed using paired t-tests.
Herein, using commonalities in expression between tissue types and evidence of cis regulation, we have identified a subset of genes whose expression is highly related to germline variation in multiple tissues.
First, the lethal thermal dose differs between tissue types and has not been established for tumour tissue of various types.
The DP3 DP4 ratios varied between tissue types and across developmental stages, and ranged from 2.4 to 3.0 1.
These studies provided the initial proof of principle that DNA methylation patterns are different between tissue types and between tumors and normal surrounding tissue.
More suggestions(16)
between tissue collection and
between management type and
between tissue stiffness and
between sample type and
between tissue structure and
between tissue hydration and
between blood type and
between picture type and
between symbiont type and
between tissue injury and
between tissue repair and
between fracture type and
between tissue engineering and
between tissue damage and
between item type and
between tissue specificity and
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