Your English writing platform
Discover LudwigExact(5)
The result is a push-pull system between tip and stalk cells.
(D ) Quantification of the number of synchronous and asynchronous Ca2+ rise between tip and stalk cells.
Another way of representing observed differences in cell number between tip and stalk cells, would be to change the rate of proliferation, and keep the probability uniform.
These observations reveal a heterogeneous requirement for Wnt/β-catenin signaling among ECs during brain invasion in zebrafish, and they predict a similar differential requirement between tip and stalk cells in the mammalian brain and retina.
Since new "matter" is added only at the front between tip and stalk to account for the local growth at the tip, protein concentrations are not diluted in this process and stay at the same absolute position.
Similar(55)
During active angiogenesis, formation and growth of new sprouts involve coordination between opposing tip and stalk cell behaviors, a process that is tightly regulated by the VEGF and Notch signaling pathways (Hellström et al., 2007; Siekmann and Lawson, 2007; Jakobsson et al., 2010).
This model centers on the interplay between tip cell and stalk cells (Eilken and Adams, 2010; Gerhardt et al., 2003; Siekmann and Lawson, 2007).
In reality, those "tasks" are divided between tip cells and stalk cells.
We do not distinguish between tip cells and stalk cells in the present model, so all cells outside the parent vessel can proliferate.
For sprout extension and maintenance of the tip cell/stalk cell differentiation, the signaling difference between two cells (e.g. a tip and stalk cell [ 70]) may be more relevant.
The total vessel changes in Experiments 3 and 4 are nearly identical, where the difference between them is only that Experiment 4 has both tip and stalk cell proliferation restricted whereas Experiment 3 has just stalk cell proliferation restricted.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com