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Because of the broad phenotypic variability both within groups and within families, delineation of genotype-phenotype correlations between these different subtypes is challenging.
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There are however biological differences between the different subtypes of HCV genotype 1, which are related to differences in their nucleotide and amino acid sequences.
Additionally, no differences were observed between the different subtypes of JIA regarding the presence of MRI-based synovial hypertrophy or bone marrow changes suggestive of bone marrow oedema.
The clinical implications for cancer vary between the different subtypes of lobular neoplasia.
A considerable distinction in metabolic activity was observed between the different subtypes of breast cancer.
The classification of breast cancer samples into these subtypes (based on the PAM50 gene signature [ 20]) is available in MEXPRESS, allowing users to compare expression, methylation and clinical data between the different subtypes.
The associations observed between the different subtypes and motives for complaint are consistent with the clinical profile-based syndrome definition, which suggests that interventions should be case-specific.
The FMS scores varied between the different subtypes (p < 0.001) and were lower with increasing distances, most pronounced in children with ataxia (Fig. 2).
Moreover, large-scale miRNA profiling of breast cancers carried out under the TCGA project has provided a comprehensive list of differentially expressed miRNAs between the different subtypes [ 56].
A considerable distinction in the SUVmax of both the primary tumour and the lymph node metastases was observed between the different subtypes of breast tumours.
Baumeister and Parker [ 34] pointed to the overlap between the different subtyping models of depression.
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