Sentence examples for between these compounds are from inspiring English sources
Thus, reactions between these compounds are controlled by dispersive mixing if they are not limited by kinetics.
The 2-D Tanimoto similarity values between these compounds are quite low, with only three compound pairs above ≥ 0.75, indicating that the 2-D similarity method based on the PubChem fingerprint fails to interrelate their common biological activity as histamine H1 receptor antagonists.
Furthermore, the low-dose combination studies with the THF-diols plus LTX-diols revealed that synergistic interactions between these compounds are unlikely.
Differences between these compounds are more evident in the toxicity profiles: neutropenia and neuropathy associated with ixabepilone (Galsky et al, 2005; Hussain et al, 2005), diarrhoea associated with patupilone (Chi et al, 2012), and neuropathy associated with sagopilone.
While the single dose curves showed increased amplitude with combinations of LND-76070 with 75654 (Fig 4A and B) and SAHA with LDN-75654 (Fig 4E), the constant ratio design suggests that the relationships between these compounds are synergistic (Fig 4G and H).
The calculated detection capabilities (CCβ) of these compounds are between 0.5 and 2.5 μg kg−1 and samples spiked at 5 μg kg−1 were found to be non-compliant based upon the ion ratio criteria [ 1] in 100% of the cases (n = 21), indicating that the method is suitable for confirmatory analysis of these antiviral drugs at relevant levels.
These data demonstrate that structural elements required for channel block by these compounds are conserved between mammals and fish.
If the relationship between these compounds were derived from a diagenetic (post depositional) degradation, then it can be assumed that alteration pathway will be the same in all samples.
A direct strategy is therefore to predict the enzyme-reaction likeness between two compounds whenever the Tanimoto similarity value between these compounds is above a threshold to be determined.
