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To test this hypothesis, we assessed the overlap between these clusters and the sets of genes that distinguish advanced, aggressive cancers from less advanced cancers.
Concordance between these clusters and the assigned species names was imperfect, in accord with the difficulties in assigning viridans group strains to species.
This study has identified five distinct, biologically plausible clusters of comorbidity, the interrelationships between these clusters and the intra-relationship between comorbidities within each cluster.
Despite a high level of genomic rearrangements, the absolute distance between these clusters and the origin of replication remains remarkably constant.
A t-test analysis (p < 0.01) was made between these clusters and revealed 1247 DEGs during the [40-80°Cdays [40-80°Cdays°Cdays] toansition and 537 DEGs during the [120-500°Cdays] transition0°Cdand] transition.
The clinical and epidemiologic characteristics of patients belonging to each of the six most common spoligotype clusters were compared between these clusters and also against all patients not in the analyzed cluster.
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The correlation in composition between some of these clusters and H3K4me should indicate a role in chromatin modulation.
In particular, a positive linear correlation was found between the activity of these clusters and the Shannon entropy of the pooled decisions reported at each task configuration.
No correlation was apparent between the identity of these clusters and their mode of regulation, i.e. G. metallireducens cluster 3 is classified as an E. coli-like cluster, and the other two do not belong to any identified class.
We found a significant positive relationship between the pBLS value of these clusters and the proportion of nucleotides in the TE chromatin state (Spearman's rank correlation coefficient: ρ = 0.480, P = 0.006; fig. 4 A).
The relationship between the level of activation in these clusters and the CIAS and BIS-11 score was examined in the IGA group using Pearson's correlation tests, but also accounting for variance of trait anxiety and depression scores.
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