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We stratified all these patients by age, i.e., 30 39, 40 49, 50 59 and over 60 years; the four islet autoantibodies did not show any statistical differences between these age subgroups.
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Although the number of participants in the ≥75 years of age subgroup who were receiving triple-combination treatment was small (n = 16), there did not appear to be any clinically relevant differences in the incidence of TEAEs between this age subgroup (overall incidence: 56 %) and the other age subgroups.
Estimates of RRs were fairly similar between age subgroups ranging between 0.981 and 0.984.
We identified significant differences in strategy use between family age subgroups, and we included strategy types in multiple linear regression models to predict differences in families with children.
A chi-square test estimated the constituent ratio of MMSE scores between different age subgroups.
Toxicity and compliance were compared between two age subgroups (<65, ≥ 65) by Fisher exact test and exact Wilcoxon rank-sum test.
For patients aged <75 years, discontinuation rates due to AEs were lower for G-GR than for placebo (6.3 vs. 10.0 %).> -wrap-foot> aIncludeventsnts reported for ≥2 % of patients in any group AE adverse event, G-GR gastroretentive gabapentin, SAE serious adverse event There was no significant difference between both age subgroups in reporting SAEs (Table 2).
There were no identified variations between the different age subgroups: under 75 years, between 76 85 years or older than 85 years or between women with or without a history of breast cancer.
Comparing the relationships between Fig. 3 A and B, we note that there is no difference between age subgroups in the shape (slope of lines at each updated, average A1C value) for the intensive (P = 0.38) or standard (P = 0.52) arms; however, the vertical positioning of the lines for the older subgroup are significantly higher within both intensive (P = 0.01) and standard (P < 0.01) arms.
The difference between age subgroups (children versus adolescents) was significant (p = 0.029).
Mean changes in the worst, least, and average pain were similar between age subgroups.
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