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The basic premises of most biomarker discovery studies is to use the high data-gathering capabilities of MS to compare biological samples obtained from healthy and disease-afflicted patients and identify proteins that are differentially abundant between the two specimen.
However, there were subtle differences between the two specimen groups regarding the growth of collagen and cartilage cells.
As a result, 485 differentially expressed probes from FNAB arrays (P < 0.001) and 258 probes from FFPE arrays (P < 0.01) were obtained, of which 39 probes (representing 38 genes) overlapped between the two specimen types.
The comparison between the two specimen types yielded lower correlation coefficients (r = 0.45), which was likely due to dominant effects on the RNA related to the tissue processing for FFPE specimens and the different hybridization techniques in DNA microarray protocols.
Given the advantages of these alternative sampling techniques and the high concordance between the two specimen types, alternative samples should nevertheless be considered for future CRS research in Sudan.
The most relevant isolated microbes in the ETT lavage fluids were also isolated by inner lumen swabs in 8/11 cases (72%), showing a good concordance between the two specimen collecting methods.
Similar(53)
Important differences between the two specimens are observed owing to the different size and amount of reinforcing steel.
X-ray diffraction analyses performed on material from the failed 25 and 950 °C specimens highlights a distinct difference in mineralogy between the two specimens that has been related to mineralogical changes in the sandstone cement with heating.
The inclination of the planum alveolare is similar between the two specimens.
The divergence between the two specimens of Barbourula busuangensis appears to have occurred during the Pleistocene.
Comparisons between the two specimens suggest that the complete sacral configuration of Melanosaurus readi includes two dorsosacrals, followed by the two primordial sacrals, and a single caudosacral (A. Yates, pers. com).
More suggestions(18)
between the two collections
between the two templates
between the two fish
between the two piece
between the two model
between the two template
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between the two display
between the two design
between the two cylinder
between the two people
between the two countries
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between the two crashes
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Justyna Jupowicz-Kozak
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