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To systematically assess the differences between the two sequencing technologies, we analyzed RNA-Seq results from amplification-based sequencing (AS) and single-molecule sequencing (SMS) across a set of twelve cancer cell lines and tissue samples.
In general, similar microbial distributions were observed between the two sequencing platforms, despite the use of different PCR primer sets and phylogenetic analysis of partially overlapping sections of the 16S rRNA sequence (Table S2).
Their investigation was instead limited to evaluating differential gene expression between the two sequencing platforms.
Although there were differences between the two sequencing methods, there were similarities in GO categories between the two transcriptomes.
If y is the overlap in nucleotides between the two sequencing traces, the cost of encoding the mutation rate is log y.
These data were used to infer the overlaps existing between the two sequencing reactions (sequencing plates) and independent libraries (i.e., 4 libraries for each sequencing plate).
Similar(52)
(Two coins from this interval between the two sequences may be easily accounted for by their happening to have been still in circulation when the building was eventually reoccupied).
Information is carried by the starting time difference between the two sequences in each symbol.
Highlighted in black are the conserved nucleotides between the two sequences.
The deposits differed between the two sequences analysed, consisting predominantly of lacustrine chalk or brown-moss sedge fen peat, respectively.
In other words, the delay between the two sequences is an integer multiple of the time slot length.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com