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However, the sensitivity varied substantially between the two registries with the stroke registry having a much higher sensitivity compared to the hospital discharge registry.
The major strength of our study was the use of two nationwide registries, the MBRN and the NorPD, and the unique 11-digit personal identity number, which ensured valid data linkage between the two registries.
The consistency of the distributions of prevalent cases and costs between the two registries is a relevant result, being a pre-requirement for extrapolation of the methodology at regional level.
Table 2 shows that based on data from the second approach, the difference in sensitivity between the two registries was even greater, ie, 91%95%5% CI 81%96%%) in the DSR and 58%95%5% CI 46%69%%) in the DNRP.
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It should be noted that GCR variable recording, including hormone receptor status, is modelled after the SEER program, though unmeasured differences may exist between the two registry programs.
11 Because the PAS for each region collects data for the DNRP, there is considerable overlap between the information accessible in the two registries.
Unfortunately, we could not discriminate between ARS and CRS in either of the two registries used.
In the two registries the GPs do not seem to differentiate between ARS and CRS, which may just be a matter of limitations of the studied registries.
The first study examined preoperative characteristics and the conclusion was that: "Baseline findings are so congruent between the NKLR and the KP ACLRR cohorts that comparisons between these two registries will likely provide information to the orthopedic community that can be generalized" (Maletis et al. 2011).
The median number of participants per study in the three registries ranged between 63 and 155.
The trial records in this study were registered between June 2008 and June 2009 on any one of the nine registries that provided data to the ICTRP Search Portal, including ClinicalTrials.gov.gov
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