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The primary comparison is then between the two randomised groups.
It may, however, not be sensitive enough to identify differences between the two randomised groups.
The primary outcome measured was the difference in wound infection rates between the two randomised groups.
Baseline demographics, cancer diagnosis, cancer stage, and treatment modalities were compared between the two randomised groups.
Baseline characteristics of patients were similar between the two randomised groups (Table 1).
There were no substantial differences between the two randomised arms on any baseline variables (Table 1).
Similar(31)
In general, the patients' characteristics were well balanced between the three randomised groups.
The two randomised trials were large.
The comparison between these two randomised trials highlights that changes in treatment modalities lead to a 12% increase of RDI, whereas the use of G-CSF is multiplied by 35 (Bonneterre et al, 2005; Roche et al, 2006).
"Disappointingly, we found no difference in the number of new infections between these two randomised sets of clusters," says Deenan Pillay, director of the Africa Centre and professor of virology at University College London.
Follow-up was also terminated in the four randomised patients.
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