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This may be due to the difference in defining "objective" assessment between the two meta-analyses.
An opposite correlation between effect size and percentage of women emerged between the two meta-analyses.
Several major differences between the two meta-analyses could explain the discrepant findings.
The differences between the two meta-analyses could be explained in different ways.
Study design and confounding probably contributed to the difference in results between the two meta-analyses presented.
The State scale of the STAI is the most used instrument in the present sample of papers and the effect sizes are similar between the two meta-analysis.
Sensitivity analyses will be reported with a summary table and review conclusions will be interpreted with concerns for comparisons between the two meta-analyses.
Their Cohen's d value of 0.16 is quite likely exaggerated by the noted publication bias and thus implies that the true difference in effect size between the two meta-analyses may be greater.
In contrast, the efficacy of LAV differed between the two meta-analyses by Villari et al. (53%; 95% CI: 35% to 66%) and Jefferson et al. (62%; 95% CI: 45% to 73%), and that by Osterholm et al. (32%; 95% CI, -2% to 55%).
For the two meta-analyses, differences between the patient subgroups were tested for statistical significance using Fisher's exact test, with Bonferroni correction to account for multiple testing [ 15]; as 139 statistical tests were carried out, the Bonferroni correction factor was 139 times the uncorrected P-value (Pcorr).
Different sets of genes were nominated across the three meta-analyses, especially between the younger and older age cohorts.
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