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Cohen's κ coefficient was 0.87, which shows a strong agreement between the two blinded observers.
The severity of barrier loss and microerosions was discrepant between the images or between the two blinded investigators the grade was calculated on the most severe changes.
The percentage agreements between the two blinded author's assessments ranged between 86% and 99% with an overall agreement of 92% (720 of the 780 total items).
At the conclusion of this process, the overall agreement between the two blinded author's scores was calculated and reported for all items.
We used Cohen's κ measure to assess the agreement between the two blinded assessors of the ulcer photographs and whether the assessors agreed with the unblinded nurse as to whether the reference ulcer had healed.
The κ (SE) values calculated between the two blinded author's assessments ranged from 0.69 (0.10) to 0.96 (0.04) which corresponded to 'substantial' or 'near-perfect' strengths of agreement for each item analysed.
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Intraclass correlation coefficient between the measurements of the two blinded radiologists was 0.94, corresponding to an outstanding inter-rater reliability.
Methodological quality of the included studies was rated by the two blinded reviewers (BL, MAL).
The primary efficacy variable was the agreement rate between Scintimun® and 99mTc-HMPAO-labelled WBCs calculated as an average across the results of the three blinded readers.
In a subset of subjects, estimates of reliability between two blinded investigators were computed based on intraclass correlation coefficients for locating the deep border of dermis, superficial border of muscle and boundary between superficial and perimuscular zones.
Table 3 Cohen's Kappa for distinguishing viral from bacterial pneumonia on lung ultrasound between two blinded sonologists Viral Pneumonia Normal Bacterial Pneumonia Viral Pneumonia 13 1 0 14 Normal 1 4 0 5 Bacterial Pneumonia 0 1 7 8 14 6 7 27 Cohen's Kappa = 0.82 95% CI (0.63 to 0.99).
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CEO of Professional Science Editing for Scientists @ prosciediting.com