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Additionally, consistency was observed between the toxicity tests and detoxification enzyme activity.
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TP performed the toxicity tests.
The oligomer fractions eluting between 55 60 ml in Fig. S4a were collected used for the toxicity test.
Consistency was found between toxicity tests and detoxification enzyme activity.
LSI performed the reproductive toxicity tests.
The embryo toxicity test procedure followed the OECD guidelines for fish embryo toxicity testing [27, 29].
As a result, a significant correlation was found between the said values in all three toxicity tests.
In addition to the dynamic changes that can occur during toxicity tests, interactions between ENMs and test organisms may lead to unexpected changes to the test organisms that could result in artifacts or misinterpretation of results if they are not appropriately considered.
The acute toxicity test also assessed.
Dosing regimen 2 was designed for the liver toxicity test.
Concentrations were selected based on the acute toxicity test results.
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