For comparisons between baseline and post-intervention, adjusted (Tukey) multiple comparisons revealed statistically significant differences between the time points for all measures in both groups; indicating improvements for both treatment groups.
For comparisons of post-intervention and 12-month follow-up; adjusted (Tukey) multiple comparisons again revealed statistically significant differences between the time points for Comprehension of Instructions for Triple P and this time for ENGAGE as well.
The mean, median, standardised deviation, and range of duration between the time points of performing the HADS and blood sampling of all subjects were 3.6, 2.0, 5.0, and 0 33 days, respectively.
Adjusted (Tukey) multiple comparisons between waitlist and baseline showed no statistically significant difference between the time points for all measures in each group; indicating that children do not simply improve on these measures over time without treatment.
Adjusted (Tukey) multiple comparisons between waitlist and baseline showed a statistically significant difference between the time points for Comprehension of Insturctions for the Triple P group; indicating that these children improved on this measures over time without treatment.
There was no difference between the time points.
Statistical difference between the time points and between A15 and MnP1-1 are indicated.
Treatment changes were evaluated between the time points using 39 variables by means of paired t test.
Treatment effects refer to the difference in mean changes between the time points of the treated and untreated control groups.
There is also a dummy (μ t ) representing general change between the time points, and an error term, ε cti.
However 3 patients had higher doses of noradrenaline (>0.075 μg/kg/min) and changes in noradrenaline between the time points.
